WebFokas has written about symmetries, integrable nonlinear PDEs, Painleve equations and random matrices, models for leukemia and protein folding, electro-magneto … WebWe discuss how early and intermediate endpoints, including patient-reported outcomes and involvement of patients in decision making, can be used to guide trial design and …
Key questions to ask when selecting outcome measures: a …
WebMay 5, 2024 · Patient-reported outcome measures (PROMs) are questionnaires that collect health outcomes directly from the people who experience them. This review critically synthesizes information on generic and selected condition-specific PROMs to describe trends and contemporary issues regarding their development, validation and application. … WebHowever, standardization of the key outcome measures of organ preservation strategies is currently lacking; this includes a lack of consensus of the optimal definitions and selection of primary end points according to the trial phase and design; the optimal time points for response assessment; response-based decision-making; follow-up schedules ... spotlight mattress protector
Outcome measures in multimodal rectal cancer trials
WebJul 25, 2016 · Abstract Tumour hypoxia renders cancer cells resistant to cancer therapy, resulting in markedly worse clinical outcomes. To find clinical candidate compounds that reduce hypoxia in tumours, we conduct a high-throughput screen for oxygen consumption rate (OCR) reduction and identify a number of drugs with this property. WebOutcome measures used as secondary endpoints (no colour). Different preoperative treatment options are characterised by variable length and time to surgery (grey). … WebApr 11, 2024 · In this paper, the Fokas-Lenells equations are investigated via bilinear approach. We bilinearize the unreduced Fokas-Lenells system, derive double Wronskian … shenette zachary