WebMar 30, 2024 · Biliary sludge is made up of precipitates of cholesterol monohydrate crystals, calcium bilirubinate, calcium phosphate, calcium carbonate, and calcium salts of fatty acids, which are embedded in biliary mucin to form sludge. ... has been identified with the use of certain medications, primarily ceftriaxone. [9, 10] WebCeftriaxone is eliminated partly in the bile, partly in the urine. Soon after it came on the market, it was shown sonographically that it could precipitate in the gallbladder [15 ], and “biliary sludge” or biliary pseudolithiasis, is now a well-known adverse effect.
Ceftriaxone‐associated biliary pseudolithiasis in children: do we …
WebCeftriaxone is a third generation cephalosporin with a broad spectrum of activity against many Gram-positive and ... Biliary sludging and pseudocholelithiasis, pancytopenia with prolonged use and higher doses (e.g., 2 g IV Q12H), hypersensitivity, C. difficile infection. WebCeftriaxone is eliminated partly in the bile, partly in the urine and can precipitate in the gallbladder [143 ], causing “biliary sludge” or biliary pseudolithiasis. This effect of ceftriaxone can occur at doses as low as 50 mg/kg/day [ 144] but is rarely symptomatic. cpu i3 4170
Ceftriaxone-Associated Biliary Complications of …
WebFeb 15, 2024 · Both pseudocholelithiasis (biliary "sludging") and true cholelithiasis (ceftriaxone-containing gallstone) have been reported in association with doses greater … WebFeb 5, 2024 · Although patient 1 received a relatively high dose of ceftriaxone (2 g for 13 days) and exhibited a high level of biliary sludge (Fig. 2a), she was asymptomatic. Patient 8 was re-administered ceftriaxone for a longer period (11 vs. 14 days) and had a pseudolithiasis relapse; however, the second episode was less severe, with no … WebFeb 16, 2024 · Ceftriaxone was discontinued and switched to cefotaxime 2 g every four hours. Hepatic transaminases started declining after ceftriaxone discontinuation and … cpu i3 4gb